Author Michael Pollan joins Oprah Winfrey to discuss the therapeutic potential of psychedelics like psilocybin and LSD for treating PTSD, depression, and anxiety. Pollan shares compelling research and moving personal stories (including tech entrepreneur Bob Parsons’ experience) illustrating how guided psychedelic experiences can alleviate trauma and spark profound spiritual insight. This thoughtful conversation demystifies psychedelics and frames them as powerful tools – when used responsibly – to achieve elevated states of awareness, process deep emotions, and even find peace with mortality.